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|Education||:||Ph.D.-- Graduate Institute of Pharmaceutical Sciences, College of Medicine, National Taiwan University 1990-1995|
Dissertation: Synthesis and Pharmacology of Novel Non-peptide Opioids. Advisor: Dr. Chen-Yu Cheng
B.S. -- School of Pharmacy, College of Medicine, National Taiwan University 1986-1990
|Experience||:||2002~ Assistant Professor(School of Pharmacy, College of Medicine, National Taiwan University)|
2001-2002 Instructor(School of Pharmacy, College of Medicine, National Taiwan University)
1997-2000 Fogarty Fellow
Sponsor: Dr. Kenner C. Rice; Laboratory of Medicinal Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health Bethesda, Maryland, USA
Design, synthesis, and structure-activity relationships of non-peptide corticotropin-releasing hormone receptor antagonists.
The development of chiral derivatives of GBR 12909 and GBR 12935 as potential cocaine abuse therapeutic agents.
Synthesis of radiopharmaceuticals as potential PET and SPECT imaging agents.
1995-1997 Pharmaceutical Analysis Scientist
The Analytical Center of Medical Supplies
National Defense Medical Center Taipei, Taiwan
Quantitative and qualitative analyses of prescription drugs and other medical supplies.
The development of antidotes for the treatment of neurotoxic agent intoxication.
Synthesis of opioid receptor antagonists for pharmacological studies.
|Research Areas||:||Medicinal Chemistry, Pharmaceutical Analysis, Molecular Imaging Agents|
|Lab Focus||:||1. Design and synthesis of novel molecular imaging agents and radiopharmaceutics|
2. Discovery and development of highly selective and potent CNS-acting drugs
3. Discovery of novel anticancer and antiviral agents utilizing asymmetric synthesis and combinatorial chemistry
4. Analysis, identification, and preparation of reference standards for novel counterfeit and illegal drugs
5. Scale up synthesis and process development for candidate drugs