1. Leu WJ, Swain SP, Chan SH, Hsu JL, Liu SP, Chan ML, Yu CC, Hsu LC, Chou YL, Chang WL, Hou DR, Guh JH. Non-immunosuppressive triazole-based small molecule induces anticancer activity against human hormone-refractory prostate cancers: The role in inhibition of PI3K/AKT/mTOR and c-Myc signaling pathways. Oncotarget 2016;7:76995¬-77009.

2. Lai WT, Cheng KL, Baruchello R, Rondanin R, Marchetti P, Simoni D, Lee RM, Guh JH, Hsu LC. Hemiasterlin derivative (R)(S)(S)-BF65 and Akt inhibitor MK-2206 synergistically inhibit SKOV3 ovarian cancer cell growth. Biochem Pharmacol 2016;113:12-23.

3. Marchetti P, Pavan B, Simoni D, Baruchello R, Rondanin R, Mischiati C, Feriotto G, Ferraro L, Hsu LC, Lee RM, Dalpiaz A. A novel hybrid drug between two potent anti-tubulin agents as a potential prolonged anticancer approach. Eur J Pharm Sci 2016;91:50-63.

4. Tsou SH, Hou MH, Hsu LC, Chen TM, Chen YH. Gain-of-function p53 mutant with 21-bp deletion confers susceptibility to multidrug resistance in MCF-7 cells. Int J Mol Med 2016;37:233-242.

5. Chan ML, Liang JW, Hsu LC, Chang WL, Lee SS, Guh JH. Zerumbone, a ginger sesquiterpene, induces apoptosis and autophagy in human hormone-refractory prostate cancers through tubulin binding and crosstalk between endoplasmic reticulum stress and mitochondrial insult. Naunyn Schmiedebergs Arch Pharmacol 2015;388:1223-1236.

6. Chang WL, Hsu LC, Leu WJ, Chen CS, Guh JH. Repurposing of nitroxoline as a potential anticancer agent against human prostate cancer: a crucial role on AMPK/mTOR signaling pathway and the interplay with Chk2 activation. Oncotarget 2015;6:39806-39820.

7. Ho CH, Hsu JL, Liu SP, Hsu LC, Chang WL, Chao CCK, Guh JH. Repurposing of phentolamine as a potential anticancer agent against human castration-resistant prostate cancer: A central role on microtubule stabilization and mitochondrial apoptosis pathway. Prostate 2015;75:1454-1466.

8. Hsu JL, Liu FL, Hsu LC, Chang HS, Leu WJ, Yu CC, Chang WL, Chen IS, Kung FL, Guh JH. Epi-reevesioside F inhibits Na+/K+-ATPase, causing cytosolic acidification, Bak activation and apoptosis in glioblastoma. Oncotarget 2015;6: 24032-24046.

9. Wu KC, Lu YH, Peng YH, Hsu LC, Lin CJ. Effects of lipopolysaccharide on the expression of plasma membrane monoamine transporter (PMAT) at the blood-brain barrier and its implications to the transport of neurotoxins. J Neurochem 2015;135:1178-1188.

10. Lin YH, Chen BYH, Lai WT, Wu SF, Guh JH, Cheng AL, Hsu LC. The Akt inhibitor MK-2206 enhances the cytotoxicity of paclitaxel (taxol) and cisplatin in ovarian cancer cells. Naunyn Schmiedebergs Arch Pharmacol 2015;388:19-31.

11. Chen BYH, Huang CH, Lin YH, Huang CC, Deng CX, Hsu LC. The K898E germline variant in the PP1-binding motif of BRCA1 causes defects in DNA repair. Sci Rep 2014;4:5812.

12. Hsu JL, Liu SP, Lee CC, Hsu LC, Ho YF, Huang HS, Guh JH. A unique amidoanthraquinone derivative displays antiproliferative activity against human hormone-refractory metastatic prostate cancers through activation of LKB1-AMPK-mTOR signaling pathway. Naunyn Schmiedebergs Arch Pharmacol 2014;387:979-990.

13. Leu WJ, Chang HS, Chan SH, Hsu JL, Yu CC, Hsu LC, Chen IS, Guh JH. Reevesioside A, a cardenolide glycoside, induces anticancer activity against human hormone-refractory prostate cancers through suppression of c-myc expression and induction of G1 arrest of the cell cycle. PLos One 2014;9:e87323.

14. Wang WT, Chen YH, Hsu JL, Leu WJ, Yu CC, Chan SH, Ho YF, Hsu LC, Guh JH. Terfenadine induces anti-proliferative and apoptotic activities in human hormone-refractory prostate cancer through histamine receptor-independent Mcl-1 cleavage and Bak up-regulation. Naunyn Schmiedebergs Arch Pharmacol 2014;387:33-45.

15. Chan SH, Leu WJ, Hsu LC, Chang HS, Hwang TL, Chen I-S, Chen C-S, Guh JH. Reevesioside F induces potent and efficient anti-proliferative and apoptotic activities through Na(+)/K(+)-ATPase alpha3 subunit-involved mitochondrial stress and amplification of caspase cascades. Biochem Pharmacol 2013;86:1564-1575.

16. Lin TS, Liw YW, Song JS, Hsieh TC, Yeh HW, Hsu LC, Lin CJ, Wu SH, Liang PH. Synthesis and biological evaluation of novel C-aryl D-glucofuranosides as sodium-dependent glucose co-transporter 2 inhibitors. Bioorg Med Chem 2013;21:6282-6291.

17. Chang HC, Yang SF, Huang CC, Lin TS, Liang PH, Lin CJ, Hsu LC. Development of a novel non-radioactive cell-based method for the screening of SGLT1 and SGLT2 inhibitors using 1-NBDG. Mol Biosyst 2013;9:2010-2020.

18. Yu CC, Wu PJ, Hsu JL, Ho YF, Hsu LC, Chang YJ, Chang HS, Chen IS, Guh JH. Ardisianone, a natural benzoquinone, efficiently induces apoptosis in human hormone-refractory prostate cancers through mitochondrial damage stress and survivin downregulation. Prostate 2013;73:133-145.

19. Hsu LC, Durrant DE, Huang CC, Chi NW, Baruchello R, Rondanin R, Rullo C, Marchetti P, Grisolia G, Simoni D, Lee RM. Development of hemiasterlin derivatives as potential anticancer agents that inhibit tubulin polymerization and synergize with a stilbene tubulin inhibitor. Invest New Drugs 2012;30:1379-1388.

20. Hsu JL, Leong PK, Ho YF, Hsu LC, Lu PH, Chen CS, Guh JH. Pim-1 knockdown potentiates paclitaxel-induced apoptosis in human hormone-refractory prostate cancers through inhibition of NHEJ DNA repair. Cancer Lett 2012;319:214-222.

21. Hsu JL, Ho YF, Li TK, Chen CS, Hsu LC, Guh JH. Rottlerin potentiates camptothecin-induced cytotoxicity in human hormone refractory prostate cancers through increased formation and stabilization of topoisomerase I-DNA cleavage complexes in a PKCδ-independent pathway. Biochem Pharmacol 2012;84:59-67.

22. Yu YM, Pace SM, Allen SR, Deng CX, Hsu LC. A PP1-binding motif present in BRCA1 plays a role in its DNA repair function. Int J Biol Sci 2008;4:352-361.

23. Hsu LC. Identification and functional characterization of a PP1-binding site in BRCA1. Biochem Biophys Res Commun 2007;360:507-512.

24. Parikh RA, White JS, Huang X, Schoppy DW, Baysal BE, Baskaran R, Bakkenist CJ, Saunders WS, Hsu LC, Romkes M, Gollin SM. Loss of distal 11q is associated with DNA repair deficiency and reduced sensitivity to ionizing radiation in head and neck squamous cell carcinoma. Genes Chromosomes Cancer 2007;46:761-775.

25. Wilcox CB, Feddes GO, Willet-Brozick JE, Hsu LC, DeLoia JA, Baysal BE. Coordinate up-regulation of TMEM97 and cholesterol biosynthesis genes in normal ovarian surface epithelial cells treated with progesterone: implications for pathogenesis of ovarian cancer. BMC Cancer 2007;7:223.

26. Hsu LC, Huang X, Seasholtz S, Potter DM, Gollin SM. Gene amplification and overexpression of protein phosphatase 1alpha in oral squamous cell carcinoma cell lines. Oncogene 2006;25:5517-5526.

27. Hsu LC, Kapali M, DeLoia JA, Gallion HH. Centrosome abnormalities in ovarian cancer. Int J Cancer 2005;113:746-751.

28. Hsu LC, Lee RM, White RL. The HPV16 E6/E7 oncogene sensitizes human ovarian surface epithelial cells to low-dose but not high-dose 5-FU and 5-FUdR. Biochem Biophys Res Commun 2004;320:249-255.

29. Liu Y, Virshup DM, White RL, Hsu LC. Regulation of BRCA1 phosphorylation by interaction with protein phosphatase 1alpha. Cancer Res 2002;62:6357-6361.

30. Hsu LC, Doan TP, White RL. Identification of a gamma-tubulin-binding domain in BRCA1. Cancer Res 2001;61:7713-7718.

31. Shepel LA, Lan H, Brasic GM, Gheen ME, Hsu LC, Haag JD, Gould MN. Mapping of 55 new rat microsatellite markers from chromosome-specific libraries. Mammalian Genome 1998;9:622-628.

32. Hsu LC, White, RL. BRCA1 is associated with the centrosome during mitosis. Proc Natl Acad Sci USA 1998;95:12983-12988.

33. Haag JD, Hsu, LC, Newton MA, Gould MN. Allelic imbalance in mammary carcinomas induced by either 7,12-dimethylbenz[a]anthracene or ionizing radiation in rats carrying genes conferring differential susceptibilities to mammary carcinogenesis. Mol Carcinogenesis 1996;17:134-143.

34. Shepel LA, Morrissey LW, Hsu LC, Gould MN. Bivariate flow karyotyping, sorting, and peak assignment of all rat chromosomes. Genomics 1994;19:75-85.

35. Hsu LC, Kennan WS, Shepel LA, Jacob HJ, Szpirer C, Szpirer J, Lander ES, Gould MN. Genetic identification of Mcs-1, a rat mammary carcinoma suppressor gene. Cancer Res 1994;54:2765-2770.

36. Hsu LC, Gould MN. Cloning and characterization of overexpressed genes in the mammary gland of rat strains carrying the mammary carcinoma suppressor (Mcs) gene. Cancer Res 1993;53:5766-5774.

37. Hsu LC, Gould, MN. Molecular cloning of Copenhagen rat Krev-1 and rap1B cDNAs and study of their association with mammary tumor resistance in the Copenhagen rat. Carcinogenesis 1991;12:533-536.

38. Hong HJ, Hsu LC, Gould MN. Molecular cloning of rat Krev-1 cDNA and analysis of the mRNA levels in normal and NMU-induced mammary carcinomas. Carcinogenesis 1990;11:1245-1247.